Extract structural model parameter estimates and associated information from a NONMEM output object.

Extract structural model parameter estimates and associated information from a NONMEM output object.

Usage

get_theta(x, output = "est", sigdig = 6, sep = "-", est.step = NULL)

Arguments

x

A NONMEM output object generated using read_nm.

output

A flag specifying the matrix or matrices to be output. Valid flag values are est (the default), se, rse, 95ci, or all.

sigdig

Specifies the number of significant digits to be provided (default=6).

sep

Specifies the separator character to use for 95% confidence intervals (default="-").

est.step

Specifies which estimation step to return parameters from (default is the last).

Value

A named vector of NONMEM model parameter estimates, or in the case of all, a list of named vectors.

Details

Output options are as follows: est returns a vector of THETA values. se returns a vector of THETA standard errors. rse returns a vector of THETA relative standard errors (se/est*100). 95ci returns a vector of the asymptotic 95% confidence intervals for the elements of THETA (est +/- 1.96*se). all returns all available THETA information as a list of named vectors.

See also

NONMEM (https://www.iconplc.com/solutions/technologies/nonmem)

Author

Justin Wilkins, justin.wilkins@occams.com

Examples

if (FALSE) { # \dontrun{
 nmOutput <- read_nm("run315.xml")
 thetas <- get_theta(nmOutput)
} # }